Nature Reviews Drug Discovery | Target Identification and Assessment in the Era of AI
Source: The Manila times
Published on: 2026-04-22 13:43
CAMBRIDGE, Mass., April 22, 2026 /PRNewswire/ -- Target identification is the first and perhaps most critical step in drug discovery and development. Although the human genome contains roughly 20,000 protein-coding genes, only about 4,500 are considered "druggable," and notably, all approved drugs to date act on only 716 distinct targets. The challenge in identifying a therapeutic target gene that both effectively treats disease and can be safely targeted has thus led to traditional methods of developing a therapeutic hypothesis taking months to decades. Today, artificial intelligence (AI) is reshaping this process, turning what was once a series of chance or random discoveries into a systematic, data-driven science. As a pioneer in AI-enabled target discovery, Insilico Medicine ("Insilico", 3696.HK), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company ...
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